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Interestingly, adult mice with modest isolated elevations in GH and IGF-1 levels have greater lean mass, improved lipid oxidation and glucose clearance 38 , while specific, temporal reductions in GH and IGF-1 in adults have been linked to deleterious metabolic effects, including impaired hepatic insulin action 38 , and reduced -cell mass and function 39
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Those benefits are attributed to the active substances biflavones, terpene trilactones (ginkgolides), flavonol glycosides, and proanthocyanidins [319, 320]
When an antioxidant like glutathione neutralizes a free radical, it becomes "oxidized." In this state, it is like a spent batteryit has done its job, but it can no longer provide protection
Public Health 63 , 165176 (2018)
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